Kratom linked to outsized proarrhythmic risks

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Over-the-counter agents used improperly to curb opioid withdrawal or induce high-dose euphoria were linked to a disproportionate number of lethal arrhythmias reported to national pharmacovigilance systems, the researchers found. The antidiarrheal drug loperamide, a weak synthetic opioid, was significantly associated with ventricular arrhythmia (proportional reporting ratio [PRR] 3.2, 95% CI 3.0-3.4), with 37% of 1,008 … Read more

What drugs have replaced opioid painkillers? The answers may surprise you

What drugs have replaced opioid painkillers?  The answers may surprise you

If you go to the doctor complaining of pain, don’t be surprised if your doctor prescribes anti-epileptic drugs, or an antidepressant, or even plain old Tylenol or ibuprofen. As healthcare providers move away from addictive opioid painkillers, other classes of drugs with pain-relieving properties are filling the gap. A Buffalo News review of nearly 10 … Read more

Tribal nations in the United States provide publicly funded opioid treatment to those who need it most

Tribal nations in the United States provide publicly funded opioid treatment to those who need it most

Open this photo in the gallery: Brent Simcosky, director of health services for the Jamestown S’Klallam Tribe, looks on from the Jamestown Healing Clinic on Washington state’s Olympic Peninsula May 24.Nathan Vanderklippe/The Globe and Mail A man-made stream trickles a tinkling chatter past the banks of freshly embellished plants to the exposed beams and huge … Read more

Sacklers may be protected from opioid liability, appellate court rules

Sacklers may be protected from opioid liability, appellate court rules

Members of the Sackler family, the billionaire owners of Purdue Pharma, will receive full immunity from all present and future civil legal claims over their role in the company’s prescription opioid business, a federal appellate panel ruled Tuesday. The ruling gives the family the sweeping protection it has asked for for years, in exchange for … Read more